Molecular Formula | C18H29N5O4
|
Molar Mass | 379.45 |
Density | 1.243±0.06 g/cm3(Predicted) |
Melting Point | 168 °C(dec.) |
Boling Point | 715.0±60.0 °C(Predicted) |
Solubility | DMSO :59 mg/mL (155.49 mM) |
pKa | 13.75±0.46(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Physical and Chemical Properties | Bioactive Val-cit-PAB-OH is a degradable ADC linker. |
Use | The VAL-CIT-PAB is used as a reagent to prepare cell penetrating peptide GRP78 ligand for tumor cell-specific prodrug therapy, and to prepare monomethylvaline derivative ligand and antibody for cancer therapy. |